One Canal By Breakthrough sits along the Lechmere Canal and has exquisite views of the Canal Park, Boston skyline and the Charles River. The building can accommodate up to 112k sq ft of research and development spaces designed for either a single tenant or multiple tenants. One Canal by Breakthrough is a short walk to the Lechmere Green Line and connects through the First Street corridor as part of the Kendall Square life science cluster, the preeminent life science destination.